Journal: Cancers
Article Title: Predicting Additional Metastases in Axillary Lymph Node Dissection After Neoadjuvant Chemotherapy: Ratio of Positive/Total Sentinel Nodes
doi: 10.3390/cancers16213638
Figure Lengend Snippet: Patterns of SLN, SLN-R and non-SLN involvement at ALND. ( A ) Number of non-SLN affected at ALND, according to cN status at diagnosis and size of SLN metastasis in the overall population. ( B ) Pattern of non-SLN involvement after ALND, according to SLN-R cut-off ≤ 0.35. ( C ) Number of non-SLN affected at ALND, according to SLN-R cut-off ≤ 0.35 and size of SLN metastasis. ( D ) Number of non-SLN affected at ALND, according to SLN-R cut-off ≤ 0.35 within each IHC subtype. List of abbreviations: nRD—non-residual disease; RD—residual disease; IHC—immunohistochemistry; SLN—sentinel lymph node; ALND—axillary lymph node dissection; ITC—isolated tumor cells; Micro—micrometastases; Macro—macrometastases; HR—hormone receptor; + positive; − negative; TN—triple negative breast cancer. p values refer to Chi-squared tests.
Article Snippet: For clinically negative axilla (cN0) BC patients, sentinel lymph node biopsy (SLN) after NAC was proven to be feasible and safe according to NSABP-B32 trial results [ ].
Techniques: Immunohistochemistry, Dissection, Isolation